Rbd 655

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Long-range enhancement of N501Y-endowed mouse infectivity of

Herein, we report that two non-RBD mutations derived from mouse-adapted strain, Ins215KLRS in the N-terminal domain (NTD) and in the

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A neutralizing human antibody binds to the N-terminal domain of the

2020 Aug 7; 369(6504): Group 3 interacts with both S1 and S2, where subgroup 3A targets the and subgroup 3B fails to bind the

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A neutralizing human antibody binds to the N-terminal domain of the

only on the receptor binding domain (RBD) of the Spike (S) protein but also across the full Spike (S) protein. 2020 Aug doi:

S:D614G and are gateway mutations that act epistatically

Having demonstrated that promotes an open conformation of the of Wuhan-Hu-1 Spike, we next sought to evaluate the effect of the

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